KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A1
All Species:
36.36
Human Site:
S517
Identified Species:
72.73
UniProt:
O95782
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95782
NP_570603.2
977
107546
S517
L
I
A
G
D
P
R
S
S
P
P
V
Q
F
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115458
977
107553
S517
L
I
A
G
D
P
R
S
S
P
P
V
Q
F
S
Dog
Lupus familis
XP_541490
922
101289
K497
I
N
L
F
P
E
T
K
A
T
I
Q
G
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P17426
977
107646
S517
L
I
A
G
D
P
R
S
S
P
P
V
Q
F
S
Rat
Rattus norvegicus
P18484
938
104026
S516
L
I
A
G
D
P
R
S
S
P
L
I
Q
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
S516
L
I
A
G
D
P
R
S
S
P
L
I
Q
F
N
Frog
Xenopus laevis
NP_001089303
939
104392
S517
L
I
A
G
D
P
R
S
S
P
L
I
Q
F
N
Zebra Danio
Brachydanio rerio
XP_001922441
959
106027
S517
L
I
A
G
D
P
R
S
S
P
L
V
Q
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
S517
L
I
A
G
D
S
R
S
A
P
L
V
Q
F
K
Honey Bee
Apis mellifera
XP_394621
937
104937
S517
L
I
A
G
D
Q
R
S
S
P
A
V
Q
F
Q
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
S516
F
I
A
G
D
E
R
S
T
A
K
I
Q
F
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
I577
S
S
L
I
T
D
R
I
S
S
A
N
L
F
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
91.3
N.A.
98.4
79.4
N.A.
N.A.
79.5
78.3
82.1
N.A.
66.6
68
62.2
N.A.
Protein Similarity:
100
N.A.
99.8
92.7
N.A.
98.8
86.9
N.A.
N.A.
87.4
87
88.1
N.A.
77.8
78.8
74.9
N.A.
P-Site Identity:
100
N.A.
100
0
N.A.
100
80
N.A.
N.A.
80
80
86.6
N.A.
73.3
80
53.3
N.A.
P-Site Similarity:
100
N.A.
100
13.3
N.A.
100
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
80
80
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
84
0
0
0
0
0
17
9
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
84
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
9
% E
% Phe:
9
0
0
9
0
0
0
0
0
0
0
0
0
92
0
% F
% Gly:
0
0
0
84
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
84
0
9
0
0
0
9
0
0
9
34
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
9
% K
% Leu:
75
0
17
0
0
0
0
0
0
0
42
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
34
% N
% Pro:
0
0
0
0
9
59
0
0
0
75
25
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
9
84
0
9
% Q
% Arg:
0
0
0
0
0
0
92
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
0
0
9
0
84
75
9
0
0
0
0
25
% S
% Thr:
0
0
0
0
9
0
9
0
9
9
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
50
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _